NVP DPP 728 dihydrochloride
NVP-DPP728 is a potent and reversible nitrile-based inhibitor of dipeptidyl peptidase IV (DPP-IV) with a Ki of 11 nM. By blocking DPP-IV-mediated GLP-1 degradation, it enhances glucose-stimulated insulin secretion. This inhibitor is a valuable research tool for studying type 2 diabetes mechanisms in both in vitro enzymatic assays and in vivo models.
Product Specifications
CAS Number
247016-69-9
Field of Research
Protein Biochemistry
Smiles
C (CNCCNC1=CC=C (C#N) C=N1) (=O) N2[C@H] (C#N) CCC2
Molecular Formula
C15H18N6O
Molecular Weight
298.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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