BMS453
BMS-189453 is a synthetic retinoid and potent RARβ-selective agonist. It acts as a testicular toxin and inhibits breast cell growth primarily by inducing active TGFβ. This compound is used in research fields such as oncology and toxicology for in vitro and in vivo studies of retinoid signaling and TGFβ-mediated growth inhibition.
Product Specifications
CAS Number
166977-43-1
Product Name Alternative
RAR/RXR, RARα, RARβ, RARγ, TGFβ, RetinoidReceptor, Retinoid Receptor, Retinoid X receptors, Retinoic acid receptors, retinoid, Inhibitor, inhibit, cell, breast, BMS 453, BMS 189453, BMS453, BMS-453, BMS189453, BMS-189453, arrest
Field of Research
Metabolism Research
Purity
99.78% (May vary between batches)
Solubility
DMSO:45 mg/mL (118.27 mM)
Smiles
CC1 (C) CC=C (c2ccccc2) c2cc (\C=C\c3ccc (cc3) C (O) =O) ccc12
Molecular Formula
C27H24O2
Molecular Weight
380.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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