GP-82996
GP-82996 (CINK4) is a selective CDK4/6 inhibitor with IC50 values of 1.5 μM (CDK4/cyclin D1) and 5.6 μM (CDK6/cyclin D1) . It induces apoptosis in U2OS osteosarcoma cells in vitro and serves as a valuable research tool for studying cell cycle dysregulation in cancer models.
Product Specifications
CAS Number
359886-84-3
Product Name Alternative
CDK4/CyclinD1, Cdk4/6 Inhibitor IV, CDK6/cycD1, CINK 4, CINK4, CINK-4, GP 82996, GP82996, GP-82996
Field of Research
Cell Biology
Purity
99.57% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.38 mM) ; DMSO:50 mg/mL (109.51 mM)
Smiles
C (N1C=2C (=CC (NC=3N=C (N[C@@H]4CC[C@@H] (O) CC4) C=C (NCC) N3) =CC2) C=C1) C5=CC=CC=C5
Molecular Formula
C27H32N6O
Molecular Weight
456.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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