PF-9184
PF-9184 is a potent and selective small molecule inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1) with an IC50 of 16.5 nM. It effectively blocks IL-1β-induced PGE2 production in vitro and is a valuable research tool for studying inflammation, pain, and cancer pathways in cellular models.
Product Specifications
CAS Number
1221971-47-6
Product Name Alternative
MPGES-1, ProstaglandinReceptor, Prostaglandin Receptor, PF-9184, PF9184, PF 9184
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
97.43% (May vary between batches)
Solubility
DMSO:60 mg/mL (130.06 mM)
Smiles
OC1=C (NS (=O) (=O) c2ccccc12) C (=O) Nc1ccc (cc1) -c1ccc (Cl) c (Cl) c1
Molecular Formula
C21H14Cl2N2O4S
Molecular Weight
461.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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