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AG-370

AG 370 is an indole tyrphostin compound that potently inhibits PDGF-induced mitogenesis with an IC50 of 20 μM, while showing only weak activity against the EGF receptor. This selective inhibitor is a valuable research tool for studying PDGF signaling pathways in cellular proliferation assays and related in vitro research models.

Product Specifications

CAS Number

134036-53-6

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

C (=C (C (=C (C#N) C#N) N) C#N) C=1C=C2C (=CC1) NC=C2

Molecular Formula

C15H9N5

Molecular Weight

259.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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