CRT5
CRT5 is a potent, selective pyrazine benzamide inhibitor of PKD isoforms (IC50s 1-2 nM) . It blocks VEGF-induced phosphorylation of HDAC5, CREB, and HSP27, and inhibits endothelial cell migration, proliferation, and tubulogenesis in vitro, making it a valuable research tool for studying angiogenesis and PKD signaling pathways.
Product Specifications
CAS Number
1034297-58-9
Field of Research
Cell Biology, Metabolism Research
Smiles
NC1=C (C=C (C=N1) C2=CC (C (NCCN (C) C) =O) =CC=C2) C3=CC4=C (C=C3) C=C (OCC) C=C4
Molecular Formula
C28H30N4O2
Molecular Weight
454.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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