ACT 335827
ACT-335827 is a selective, brain-penetrant orexin-1 receptor (OX1R) antagonist with oral bioavailability, exhibiting IC50 values of 6 nM for OX1R and 417 nM for OX2R. It is a valuable research tool for investigating the role of the orexin system in neurological disorders such as anxiety, addiction, and insomnia in both in vitro and in vivo models.
Product Specifications
CAS Number
1354039-86-3
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C ([C@H]1C=2C (=CC (OC) =C (OC) C2) CCN1[C@@H] (C (NC (C) C) =O) C3=CC=CC=C3) C4=CC (OC) =C (OC) C=C4
Molecular Formula
C31H38N2O5
Molecular Weight
518.64
Storage Conditions
-20°C
Notes
For research use only.
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