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ACT 335827

ACT-335827 is a selective, brain-penetrant orexin-1 receptor (OX1R) antagonist with oral bioavailability, exhibiting IC50 values of 6 nM for OX1R and 417 nM for OX2R. It is a valuable research tool for investigating the role of the orexin system in neurological disorders such as anxiety, addiction, and insomnia in both in vitro and in vivo models.

Product Specifications

CAS Number

1354039-86-3

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

C ([C@H]1C=2C (=CC (OC) =C (OC) C2) CCN1[C@@H] (C (NC (C) C) =O) C3=CC=CC=C3) C4=CC (OC) =C (OC) C=C4

Molecular Formula

C31H38N2O5

Molecular Weight

518.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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