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AEG 3482

AEG 3482 is a cell-permeable small molecule that acts as a potent antiapoptotic agent by binding HSP90. This interaction promotes HSF1-mediated upregulation of HSP70, which subsequently inhibits JNK activity. It is utilized in research to study apoptosis, heat shock response, and neuroprotection in both cellular and animal models.

Product Specifications

CAS Number

63735-71-7

Product Name Alternative

Apoptosis, AEG 3482, AEG3482, AEG-3482

Field of Research

Cell Biology, Signal Transduction

Purity

99.76% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (17.84 mM) ; DMSO:200 mg/mL (713.44 mM)

Smiles

NS (=O) (=O) c1nn2cc (nc2s1) -c1ccccc1

Molecular Formula

C10H8N4O2S2

Molecular Weight

280.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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