AEG 3482
AEG 3482 is a cell-permeable small molecule that acts as a potent antiapoptotic agent by binding HSP90. This interaction promotes HSF1-mediated upregulation of HSP70, which subsequently inhibits JNK activity. It is utilized in research to study apoptosis, heat shock response, and neuroprotection in both cellular and animal models.
Product Specifications
CAS Number
63735-71-7
Product Name Alternative
Apoptosis, AEG 3482, AEG3482, AEG-3482
Field of Research
Cell Biology, Signal Transduction
Purity
99.76% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (17.84 mM) ; DMSO:200 mg/mL (713.44 mM)
Smiles
NS (=O) (=O) c1nn2cc (nc2s1) -c1ccccc1
Molecular Formula
C10H8N4O2S2
Molecular Weight
280.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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