CDP 840 hydrochloride

CDP-840 (GR259653X) is a potent, selective, and orally active phosphodiesterase 4 (PDE4) inhibitor. It demonstrates efficacy in preclinical asthma models by selectively suppressing antigen-induced bronchoconstriction in conscious squirrel monkeys. This compound is a valuable research tool for investigating PDE4 biology and inflammatory airway diseases in both in vitro and in vivo experimental systems.