AMG-25
AMG-25 (c-Kit-IN-5-1) is a potent, selective c-Kit inhibitor with additional activity against KDR, p38, Lck, and Src kinases. It serves as a valuable research tool for investigating mast cell-driven pathologies, including fibrosis, in both cellular and animal model studies.
Product Specifications
CAS Number
1003311-62-3
Product Name Alternative
SCFR, CD117, cKit, c-Kit, cKitIN51, c-Kit-IN-5-1, 3- (2-Aminoquinazolin-6-yl) -4-methyl-1- (4- (oxazol-2-yl) phenyl) pyridin-2 (1H) -one, 3- (2-aminoquinazolin-6-yl) -4-methyl-1-[4- (1,3-oxazol-2-yl) phenyl]pyridin-2-one, AMG 25, AMG25, AMG-25, c Kit IN 5 1, mast, fibrotic
Field of Research
Signal Transduction
Purity
98.16% (May vary between batches)
Solubility
DMSO:20 mg/mL (50.58 mM)
Smiles
Cc1ccn (-c2ccc (cc2) -c2ncco2) c (=O) c1-c1ccc2nc (N) ncc2c1
Molecular Formula
C23H17N5O2
Molecular Weight
395.41
Storage Conditions
-20°C
Notes
For research use only.
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