Nilotinib hydrochloride
Nilotinib hydrochloride is an orally bioavailable Bcr-Abl tyrosine kinase inhibitor used in chronic myelogenous leukemia research. It has demonstrated activity in preclinical studies investigating neuroinflammation and cognitive deficits, showing potential in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
923288-95-3
Product Name Alternative
Nilotinib Hydrochloride, AMN-107 HCl, Autophagy, BcrAbl, Bcr-Abl
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.98% (May vary between batches)
Solubility
DMSO:90 mg/mL (159.02 mM) ; Ethanol:1 mg/mL (1.77 mM)
Smiles
Cl.O=C (NC=1C=C (C=C (C1) C (F) (F) F) N2C=NC (=C2) C) C3=CC=C (C (=C3) NC=4N=CC=C (N4) C5=CN=CC=C5) C
Molecular Formula
C28H23ClF3N7O
Molecular Weight
565.98
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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