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S107 hydrochloride

S107 hydrochloride is a RyR-selective 1,4-benzothiazepine derivative that stabilizes the RyR2 channel by increasing the binding affinity of calstabin2. This action is particularly relevant for studying mutant or PKA-phosphorylated channels in cardiovascular research, with applications in both in vitro and in vivo models of conditions like catecholaminergic polymorphic ventricular tachycardia (CPVT) .

Product Specifications

CAS Number

1357476-46-0

Smiles

Cl.COc1ccc2SCCN (C) Cc2c1

Molecular Formula

C11H16ClNOS

Molecular Weight

245.77

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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