UK-371804 HCl
UK-371804 is a highly potent and selective small molecule inhibitor of urokinase-type plasminogen activator (uPA), exhibiting a Ki of 10 nM. It demonstrates significant selectivity, being 2700-fold more selective against plasmin and 4000-fold against tissue-type plasminogen activator (tPA) . This inhibitor is a valuable research tool for studying uPA's role in cancer cell invasion, metastasis, and angiogenesis in both in vitro and in vivo models.
Product Specifications
CAS Number
256476-36-5
Field of Research
Metabolism Research, Protein Biochemistry
Smiles
Cl.CC (C) (NS (=O) (=O) c1ccc2c (Cl) cnc (NC (N) =N) c2c1) C (O) =O
Molecular Formula
C14H17Cl2N5O4S
Molecular Weight
422.29
Storage Conditions
-20°C
Notes
For research use only.
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