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Alendronate sodium

This small molecule is a potent inhibitor of human farnesyl diphosphate synthase (FPPS; IC50 = 460 nM), a key enzyme in the mevalonate pathway. It induces macrophage apoptosis and disrupts protein prenylation and sterol biosynthesis in osteoclasts, making it a valuable research tool for studying bone resorption, immune cell biology, and metabolic disorders in cellular models.

Product Specifications

CAS Number

129318-43-0

Purity

99.94% (May vary between batches)

Smiles

O=P (C (P (O) ([O-]) =O) (O) CCCN) (O) O.[Na+]

Molecular Formula

C4H12NNaO7P2

Molecular Weight

271.08

Storage Conditions

-20°C

Notes

For research use only.

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