Alendronate sodium
This small molecule is a potent inhibitor of human farnesyl diphosphate synthase (FPPS; IC50 = 460 nM), a key enzyme in the mevalonate pathway. It induces macrophage apoptosis and disrupts protein prenylation and sterol biosynthesis in osteoclasts, making it a valuable research tool for studying bone resorption, immune cell biology, and metabolic disorders in cellular models.
Product Specifications
CAS Number
129318-43-0
Purity
99.94% (May vary between batches)
Smiles
O=P (C (P (O) ([O-]) =O) (O) CCCN) (O) O.[Na+]
Molecular Formula
C4H12NNaO7P2
Molecular Weight
271.08
Storage Conditions
-20°C
Notes
For research use only.
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