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ALK5 Inhibitor II (hydrochloride)

ALK5 Inhibitor II is a potent and selective inhibitor of ALK5 kinase, with IC50 values of 4 nM, 18 nM, and 23 nM in autophosphorylation, cellular TGF-β response, and binding assays, respectively. This compound is a valuable research tool for investigating TGF-β signaling pathways in both in vitro and in vivo models of fibrosis, cancer, and immunology.

Product Specifications

CAS Number

2319939-07-4

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

CC1=NC (C2=NNC=C2C3=NC4=CC=CN=C4C=C3) =CC=C1.Cl

Molecular Formula

C17H13N5·HCl

Molecular Weight

323.8

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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