ALK5 Inhibitor II (hydrochloride)
ALK5 Inhibitor II is a potent and selective inhibitor of ALK5 kinase, with IC50 values of 4 nM, 18 nM, and 23 nM in autophosphorylation, cellular TGF-β response, and binding assays, respectively. This compound is a valuable research tool for investigating TGF-β signaling pathways in both in vitro and in vivo models of fibrosis, cancer, and immunology.
Product Specifications
CAS Number
2319939-07-4
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
CC1=NC (C2=NNC=C2C3=NC4=CC=CN=C4C=C3) =CC=C1.Cl
Molecular Formula
C17H13N5·HCl
Molecular Weight
323.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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