(+) -Bicuculline methiodide
(+) -Bicuculline methiodide is a blood-brain barrier permeable GABAA receptor antagonist used to induce and study seizure activity in models of epilepsy. Its application extends to neuropharmacological research, where it is employed in both in vitro electrophysiology and in vivo studies investigating neurological disorders and septic pathophysiology.
Product Specifications
CAS Number
40709-69-1
Product Name Alternative
Bicuculline methiodide, () Bicuculline methiodide, () Bicuculline methiodide, d-Bicuculline methiodide, N-Methylbicuculline iodide, GABAReceptor, GABA Receptor, GABAA
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.24% (May vary between batches)
Solubility
DMSO:<25.46 mg/mL; H2O:<10.19 mg/ml
Smiles
C[N+]1 (C) [C@] ([C@]2 (C3=C (C (=O) O2) C4=C (C=C3) OCO4) [H]) (C5=C (C=C6C (=C5) OCO6) CC1) [H].[I-]
Molecular Formula
C21H20INO6
Molecular Weight
509.29
Storage Conditions
-20°C
Notes
For research use only.
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