CDK8/19-IN-51
CDK8/19-IN-51 is a potent and orally bioavailable dual inhibitor of CDK8 and CDK19, exhibiting low nanomolar IC50 values. It demonstrates anticancer activity in research models, particularly in studies focusing on colorectal and gastric cancers, and is utilized in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
1860885-61-5
Product Name Alternative
CCT251545 analogue, Compound 51, CCT-251545 analogue, Compound 51
Field of Research
Cell Biology
Purity
98.65% (May vary between batches)
Solubility
DMSO:8 mg/mL (19.3 mM)
Smiles
O=C (C1=NC2=C (C=NC (N) =C2C=C1) C3=CC=C (C=C3) C=4C=NN (C4) C) N5CC (OC) C5
Molecular Formula
C23H22N6O2
Molecular Weight
414.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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