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CDK8/19-IN-51

CDK8/19-IN-51 is a potent and orally bioavailable dual inhibitor of CDK8 and CDK19, exhibiting low nanomolar IC50 values. It demonstrates anticancer activity in research models, particularly in studies focusing on colorectal and gastric cancers, and is utilized in both in vitro and in vivo experimental settings.

Product Specifications

CAS Number

1860885-61-5

Product Name Alternative

CCT251545 analogue, Compound 51, CCT-251545 analogue, Compound 51

Field of Research

Cell Biology

Purity

98.65% (May vary between batches)

Solubility

DMSO:8 mg/mL (19.3 mM)

Smiles

O=C (C1=NC2=C (C=NC (N) =C2C=C1) C3=CC=C (C=C3) C=4C=NN (C4) C) N5CC (OC) C5

Molecular Formula

C23H22N6O2

Molecular Weight

414.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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