CFM-4
CFM 4 is a small molecule antagonist of the CARP-1/APC-2 interaction, inducing G2/M arrest and apoptosis with an IC50 of 10-15 μM. It demonstrates efficacy in suppressing the proliferation of drug-resistant breast cancer cells in vitro, supporting its investigation as a potential therapeutic agent in oncology research.
Product Specifications
CAS Number
331458-02-7
Product Name Alternative
CFM4, CFM-4, CFM 4, Apoptosis, APC
Field of Research
Cell Biology, Protein Biochemistry
Purity
>98%
Bioactivity
CARP-1 mimetic
Form
Powder
Solubility
Soluble in DMSO (greater than 25 mg/ml)
Smiles
O=C1C2 (C=3C (N1CC4=C (Cl) C=CC=C4) =CC=CC3) SC (=NN2) C5=CC=CC=C5
Molecular Formula
C22H16ClN3OS
Molecular Weight
405.90
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-[ (2-Chlorophenyl) methyl]-5'-phenyl-spiro[3H-indole-3,2' (3'H) -[1,3,4]thiadiazol]-2 (1H) -one
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