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CFM-4

CFM 4 is a small molecule antagonist of the CARP-1/APC-2 interaction, inducing G2/M arrest and apoptosis with an IC50 of 10-15 μM. It demonstrates efficacy in suppressing the proliferation of drug-resistant breast cancer cells in vitro, supporting its investigation as a potential therapeutic agent in oncology research.

Product Specifications

CAS Number

331458-02-7

Product Name Alternative

CFM4, CFM-4, CFM 4, Apoptosis, APC

Field of Research

Cell Biology, Protein Biochemistry

Purity

>98%

Bioactivity

CARP-1 mimetic

Form

Powder

Solubility

Soluble in DMSO (greater than 25 mg/ml)

Smiles

O=C1C2 (C=3C (N1CC4=C (Cl) C=CC=C4) =CC=CC3) SC (=NN2) C5=CC=CC=C5

Molecular Formula

C22H16ClN3OS

Molecular Weight

405.90

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

1-[ (2-Chlorophenyl) methyl]-5'-phenyl-spiro[3H-indole-3,2' (3'H) -[1,3,4]thiadiazol]-2 (1H) -one

Available Sizes

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