Laduviglusib trihydrochloride
Laduviglusib trihydrochloride (CT99021 trihydrochloride) is a potent and selective GSK-3 inhibitor, activating Wnt/β-catenin signaling and inducing autophagy. It is widely used in research areas such as neurodegenerative diseases, cancer, and diabetes, with applications in both cellular and animal model studies to investigate related pathways.
Product Specifications
CAS Number
1782235-14-6
Product Name Alternative
GSK-3α, GSK3, GSK-3β, Laduviglusib, Laduviglusib Trihydrochloride, 252917-06-9, 252917-06-9 free base, bcatenin, beta-catenin, CHIR 99021, CHIR 99021 Trihydrochloride, CHIR 99021 trihydrochloride, CHIR 99021 trihydrochloride (252917-06-9 free base), CHIR99021 Trihydrochloride, CHIR-99021 Trihydrochloride, CHIR99021, CHIR-99021, betacatenin, CT99021 trihydrochloride, CT99021 Trihydrochloride, CT-99021 Trihydrochloride, CT99021, CT-99021, CT 99021, CT 99021 Trihydrochloride, βcatenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, Wnt/beta-catenin
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.03% (May vary between batches)
Solubility
H2O:17.1 mg/mL (29.81 mM) ; DMSO:28.8 mg/mL (50.2 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (3.49 mM)
Smiles
Cl.Cl.Cl.Cc1cnc ([nH]1) -c1cnc (NCCNc2ccc (cn2) C#N) nc1-c1ccc (Cl) cc1Cl
Molecular Formula
C22H20Cl5N8
Molecular Weight
573.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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