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Laduviglusib trihydrochloride

Laduviglusib trihydrochloride (CT99021 trihydrochloride) is a potent and selective GSK-3 inhibitor, activating Wnt/β-catenin signaling and inducing autophagy. It is widely used in research areas such as neurodegenerative diseases, cancer, and diabetes, with applications in both cellular and animal model studies to investigate related pathways.

Product Specifications

CAS Number

1782235-14-6

Product Name Alternative

GSK-3α, GSK3, GSK-3β, Laduviglusib, Laduviglusib Trihydrochloride, 252917-06-9, 252917-06-9 free base, bcatenin, beta-catenin, CHIR 99021, CHIR 99021 Trihydrochloride, CHIR 99021 trihydrochloride, CHIR 99021 trihydrochloride (252917-06-9 free base), CHIR99021 Trihydrochloride, CHIR-99021 Trihydrochloride, CHIR99021, CHIR-99021, betacatenin, CT99021 trihydrochloride, CT99021 Trihydrochloride, CT-99021 Trihydrochloride, CT99021, CT-99021, CT 99021, CT 99021 Trihydrochloride, βcatenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, Wnt/beta-catenin

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.03% (May vary between batches)

Solubility

H2O:17.1 mg/mL (29.81 mM) ; DMSO:28.8 mg/mL (50.2 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (3.49 mM)

Smiles

Cl.Cl.Cl.Cc1cnc ([nH]1) -c1cnc (NCCNc2ccc (cn2) C#N) nc1-c1ccc (Cl) cc1Cl

Molecular Formula

C22H20Cl5N8

Molecular Weight

573.71

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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