EB-47 dihydrochloride
EB 47 is a potent small molecule inhibitor of PARP-1, exhibiting an IC50 of 45 nM. This compound is a valuable research tool for studying DNA repair mechanisms in vitro and has been utilized in preclinical cancer research models to investigate synthetic lethality and combination therapies.
Product Specifications
CAS Number
1190332-25-2
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
Cl.Cl.Nc1ncnc2n (cnc12) [C@@H]1O[C@@H] ([C@@H] (O) [C@H]1O) C (=O) N1CCN (CC (=O) Nc2cccc3C (=O) NCc23) CC1
Molecular Formula
C24H29Cl2N9O6
Molecular Weight
610.45
Storage Conditions
-20°C
Notes
For research use only.
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