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IWP 12

IWP-12 is a potent and selective small-molecule inhibitor of Porcupine (Porcn), a key enzyme in Wnt ligand secretion. By blocking the Wnt signaling pathway, it is a valuable tool for studying Wnt-dependent processes, including tissue regeneration, as demonstrated by its inhibition of fin regrowth in zebrafish models.

Product Specifications

CAS Number

688353-45-9

Product Name Alternative

IWP12, IWP-12, IWP 12

Field of Research

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.88% (May vary between batches)

Solubility

DMSO:20 mg/mL (47.78 mM)

Smiles

O=C1C=2SC (C) CC2N=C (SCC (=O) NC3=NC=4C=CC (=CC4S3) C) N1C

Molecular Formula

C18H18N4O2S3

Molecular Weight

418.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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