IWP 12
IWP-12 is a potent and selective small-molecule inhibitor of Porcupine (Porcn), a key enzyme in Wnt ligand secretion. By blocking the Wnt signaling pathway, it is a valuable tool for studying Wnt-dependent processes, including tissue regeneration, as demonstrated by its inhibition of fin regrowth in zebrafish models.
Product Specifications
CAS Number
688353-45-9
Product Name Alternative
IWP12, IWP-12, IWP 12
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.88% (May vary between batches)
Solubility
DMSO:20 mg/mL (47.78 mM)
Smiles
O=C1C=2SC (C) CC2N=C (SCC (=O) NC3=NC=4C=CC (=CC4S3) C) N1C
Molecular Formula
C18H18N4O2S3
Molecular Weight
418.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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