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JP 1302 dihydrochloride

JP1302 is a potent and selective α2C adrenoceptor antagonist (Kb = 16 nM) with demonstrated antidepressant activity. It disrupts the FACT complex, leading to histone H1 degradation, and has been utilized in research models of neuropsychiatric disorders and renal injury.

Product Specifications

CAS Number

80259-18-3

Product Name Alternative

Adrenergic Receptor, AdrenergicReceptor, JP 1302, JP 1302 dihydrochloride, JP1302, JP-1302, α2C-adrenergic receptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.48% (May vary between batches)

Solubility

H2O:insoluble; DMSO:36.85 mg/mL (100.01 mM)

Smiles

N (C=1C2=C (N=C3C1C=CC=C3) C=CC=C2) C4=CC=C (C=C4) N5CCN (C) CC5

Molecular Formula

C24H24N4

Molecular Weight

368.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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