Motesanib Diphosphate
Motesanib Diphosphate (AMG 706) is an orally administered small molecule that inhibits multiple receptor tyrosine kinases. It has been investigated in preclinical cancer research for its anti-angiogenic and anti-tumor effects in both in vitro assays and in vivo xenograft models.
Product Specifications
CAS Number
857876-30-3
Product Name Alternative
AMG 706, AMG 706 Diphosphate, AMG706, AMG-706, CD117, c-Kit, cKit, Kit, inhibit, Motesanib, Motesanib Diphosphate, Inhibitor, SCFR, Vascular endothelial growth factor receptor, VEGFR2, VEGFR1, VEGFR, VEGFR3, VEGFR2/Flk1
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.33% (May vary between batches)
Solubility
H2O:16 mg/mL (28.1 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.8 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (163.32 mM)
Smiles
OP (=O) (O) O.CC1 (C) CNc2c1ccc (NC (=O) c1c (NCc3ccncc3) nccc1) c2.OP (=O) (O) O
Molecular Formula
C22H23N5O·2H3PO4
Molecular Weight
569.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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