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Motesanib Diphosphate

Motesanib Diphosphate (AMG 706) is an orally administered small molecule that inhibits multiple receptor tyrosine kinases. It has been investigated in preclinical cancer research for its anti-angiogenic and anti-tumor effects in both in vitro assays and in vivo xenograft models.

Product Specifications

CAS Number

857876-30-3

Product Name Alternative

AMG 706, AMG 706 Diphosphate, AMG706, AMG-706, CD117, c-Kit, cKit, Kit, inhibit, Motesanib, Motesanib Diphosphate, Inhibitor, SCFR, Vascular endothelial growth factor receptor, VEGFR2, VEGFR1, VEGFR, VEGFR3, VEGFR2/Flk1

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.33% (May vary between batches)

Solubility

H2O:16 mg/mL (28.1 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.8 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (163.32 mM)

Smiles

OP (=O) (O) O.CC1 (C) CNc2c1ccc (NC (=O) c1c (NCc3ccncc3) nccc1) c2.OP (=O) (O) O

Molecular Formula

C22H23N5O·2H3PO4

Molecular Weight

569.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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