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L-168049

L-168049 is a potent, selective, and non-competitive antagonist of the human glucagon receptor, exhibiting IC50 values of 3.7 nM (human), 63 nM (murine), and 60 nM (canine) . It is a valuable research tool for studying glucose metabolism and diabetes pathophysiology in both in vitro assays and in vivo models.

Product Specifications

CAS Number

191034-25-0

Product Name Alternative

L-168,049, L168049, L-168049, human glucagon receptor, GlucagonReceptor, Glucagon Receptor, L 168049

Field of Research

Pharmacology & Drug Discovery

Purity

99.87% (May vary between batches)

Solubility

Ethanol:3.4 mM; DMSO:insoluble

Smiles

CCCOc1ccc (Br) cc1-c1cc ([nH]c1-c1ccncc1) -c1ccc (Cl) cc1

Molecular Formula

C24H20BrClN2O

Molecular Weight

467.79

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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