L-168049
L-168049 is a potent, selective, and non-competitive antagonist of the human glucagon receptor, exhibiting IC50 values of 3.7 nM (human), 63 nM (murine), and 60 nM (canine) . It is a valuable research tool for studying glucose metabolism and diabetes pathophysiology in both in vitro assays and in vivo models.
Product Specifications
CAS Number
191034-25-0
Product Name Alternative
L-168,049, L168049, L-168049, human glucagon receptor, GlucagonReceptor, Glucagon Receptor, L 168049
Field of Research
Pharmacology & Drug Discovery
Purity
99.87% (May vary between batches)
Solubility
Ethanol:3.4 mM; DMSO:insoluble
Smiles
CCCOc1ccc (Br) cc1-c1cc ([nH]c1-c1ccncc1) -c1ccc (Cl) cc1
Molecular Formula
C24H20BrClN2O
Molecular Weight
467.79
Storage Conditions
-20°C
Notes
For research use only.
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