L-365260
L-365260 is a potent, selective, and orally bioavailable nonpeptide antagonist of the gastrin/CCK-B receptor. It inhibits CCK-8S-induced calcium mobilization in vitro and blocks stress-induced visceral hypersensitivity and CCK-4-induced anxiety-like behaviors in vivo, making it a valuable research tool for studying gastrointestinal and neurological disorders.
Product Specifications
CAS Number
118101-09-0
Product Name Alternative
L 365260, L-365,260, L365260, L-365260, gastrin, CCK
Field of Research
Pharmacology & Drug Discovery
Purity
99.75% (May vary between batches)
Solubility
Ethanol:<39.85 mg/mL; DMSO:80 mg/mL (200.77 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.28 mM)
Smiles
CN1c2ccccc2C (=N[C@@H] (NC (=O) Nc2cccc (C) c2) C1=O) c1ccccc1
Molecular Formula
C24H22N4O2
Molecular Weight
398.46
Storage Conditions
-20°C
Notes
For research use only.
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