L748337
L748337 is a potent competitive antagonist of β1-, β2-, and β3-adrenoceptors. It blocks CL316243 effects, activates MAPK/Erk1/2 signaling, and is a valuable research tool for studying β3-adrenoceptor-related disorders in metabolic and cardiovascular research, applicable in both in vitro and in vivo models.
Product Specifications
CAS Number
244192-94-7
Product Name Alternative
AdrenergicReceptor, Adrenergic Receptor, L 748337, L748337, L-748337, L-748,337, β1-adrenergic receptor, β2-adrenergic receptor, β3-adrenergic receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.67% (May vary between batches)
Solubility
DMSO:80 mg/mL (160.77 mM) ; Ethanol:20 mg/mL (40.19 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.63 mM)
Smiles
CC (=O) NCc1cccc (OC[C@@H] (O) CNCCc2ccc (NS (=O) (=O) c3ccccc3) cc2) c1
Molecular Formula
C26H31N3O5S
Molecular Weight
497.61
Storage Conditions
-20°C
Notes
For research use only.
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