WHI-P97
WHI-P97 is a potent and selective JAK-3 inhibitor. WHI-P97 is effective in preventing the development allergic asthma in vivo[1].
Product Specifications
CAS Number
211555-05-4
UNSPSC
12352005
Hazard Statement
H315, H317, H319, H335
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/WHI-P97.html
Purity
99.70
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
BrC1=CC(NC2=NC=NC3=CC(OC)=C(OC)C=C32)=CC(Br)=C1O
Molecular Formula
C16H13Br2N3O3
Molecular Weight
455.10
Precautions
H315, H317, H319, H335
References & Citations
[1]R Malaviya, et al. Treatment of allergic asthma by targeting janus kinase 3-dependent leukotriene synthesis in mast cells with 4- (3', 5'-dibromo-4'-hydroxyphenyl) amino-6,7-dimethoxyquinazoline (WHI-P97) . J Pharmacol Exp Ther. 2000 Dec;295 (3) :912-26.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JAK3
Available Sizes
Frequently Asked Questions
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