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LY 456236 hydrochloride

LY 456236 hydrochloride is a potent, selective, and orally active non-competitive mGlu1 receptor antagonist (IC50=143 nM) . It also inhibits inositol phosphate hydrolysis (IC50=0.145 μM) and EGFR (IC50=0.91 μM) . This compound is a valuable research tool for studying mGlu1 receptor function in neurological disorders, with applications in both in vitro and in vivo models.

Product Specifications

CAS Number

338736-46-2

Product Name Alternative

MPMQ hydrochloride, MPMQ Hydrochloride, mGluR, LY 456236 Hydrochloride, LY456236 Hydrochloride, LY-456236 Hydrochloride, EGFR

Field of Research

Cardiovascular Research, Neuroscience, Signal Transduction

Purity

99.89% (May vary between batches)

Solubility

DMSO:225 mg/mL (708.06 mM)

Smiles

Cl.COc1ccc (Nc2ncnc3ccc (OC) cc23) cc1

Molecular Formula

C16H16ClN3O2

Molecular Weight

317.77

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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