LY 456236 hydrochloride
LY 456236 hydrochloride is a potent, selective, and orally active non-competitive mGlu1 receptor antagonist (IC50=143 nM) . It also inhibits inositol phosphate hydrolysis (IC50=0.145 μM) and EGFR (IC50=0.91 μM) . This compound is a valuable research tool for studying mGlu1 receptor function in neurological disorders, with applications in both in vitro and in vivo models.
Product Specifications
CAS Number
338736-46-2
Product Name Alternative
MPMQ hydrochloride, MPMQ Hydrochloride, mGluR, LY 456236 Hydrochloride, LY456236 Hydrochloride, LY-456236 Hydrochloride, EGFR
Field of Research
Cardiovascular Research, Neuroscience, Signal Transduction
Purity
99.89% (May vary between batches)
Solubility
DMSO:225 mg/mL (708.06 mM)
Smiles
Cl.COc1ccc (Nc2ncnc3ccc (OC) cc23) cc1
Molecular Formula
C16H16ClN3O2
Molecular Weight
317.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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