MNI 137
MNI 137 is a potent and selective negative allosteric modulator (NAM) of the metabotropic glutamate receptor 2 (mGlu2) . It effectively inhibits glutamate-induced calcium mobilization with IC50 values of 8.3 nM (human) and 12.6 nM (rat), making it a valuable research tool for investigating mGlu2 function in neuropharmacology and psychiatric disorder models.
Product Specifications
CAS Number
946619-21-2
Product Name Alternative
MNI 137, MNI137, MNI-137, mGluR2
Field of Research
Neuroscience
Purity
97.21% (May vary between batches)
Solubility
DMSO:17.06 mg/mL (50.01 mM)
Smiles
O=C1NC=2C (N=C (C1) C=3C=C (C#N) N=CC3) =CC=C (Br) C2
Molecular Formula
C15H9BrN4O
Molecular Weight
341.16
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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