N, N-Dimethylsphingosine
N, N-Dimethylsphingosine (DMS) is an endogenous, competitive inhibitor of sphingosine kinase (SphK) that selectively blocks sphingosine phosphorylation. Elevated in neuropathic pain models, it is used in research to study mechanisms of mechanical nociception, including the potentiation of IL-1β and MCP-1 release in vitro and in vivo.
Product Specifications
CAS Number
119567-63-4
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Sphingosine kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml) .
Smiles
CCCCCCCCCCCCC\C=C\[C@@H] (O) [C@H] (CO) N (C) C
Molecular Formula
C20H41NO2
Molecular Weight
327.56
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2S,3R, E) -2- (Dimethylamino) octadeca-4-ene-1,3-diol
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