N, N-Dimethylsphingosine
N, N-Dimethylsphingosine (DMS) is an endogenous, competitive inhibitor of sphingosine kinase (SphK) that selectively blocks sphingosine phosphorylation. Elevated in neuropathic pain models, it is used in research to study mechanisms of mechanical nociception, including the potentiation of IL-1β and MCP-1 release in vitro and in vivo.
Product Specifications
CAS Number
119567-63-4
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Sphingosine kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml) .
Smiles
CCCCCCCCCCCCC\C=C\[C@@H] (O) [C@H] (CO) N (C) C
Molecular Formula
C20H41NO2
Molecular Weight
327.56
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2S,3R, E) -2- (Dimethylamino) octadeca-4-ene-1,3-diol
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC210867L3V 200 µL
PCDHGB5 (NM_032099) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
K2348406 1.0 µg DNA
TCEB3CL sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
Sign In for Pricing
View Details LV685824 1.0 µg DNA
Myl6l Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)
Sign In for Pricing
View Details