N, N-Dimethylsphingosine
N, N-Dimethylsphingosine (DMS) is an endogenous, competitive inhibitor of sphingosine kinase (SphK) that selectively blocks sphingosine phosphorylation. Elevated in neuropathic pain models, it is used in research to study mechanisms of mechanical nociception, including the potentiation of IL-1β and MCP-1 release in vitro and in vivo.
Product Specifications
CAS Number
119567-63-4
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Sphingosine kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml) .
Smiles
CCCCCCCCCCCCC\C=C\[C@@H] (O) [C@H] (CO) N (C) C
Molecular Formula
C20H41NO2
Molecular Weight
327.56
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2S,3R, E) -2- (Dimethylamino) octadeca-4-ene-1,3-diol
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Lsx9458-50gEcoli 50 µg (E. coli)
Recombinant Clostridium Kluyveri CKL_2433 Protein (aa 1-106)
Sign In for Pricing
View Details 
4052300/30 1 Each
OVERHEAD PROJECTOR TRANSPARENCIES Schafer’s Method – I
Sign In for Pricing
View Details 