PB28
PB28 dihydrochloride is a dual sigma-2 receptor agonist and sigma-1 antagonist with demonstrated anti-tumor and anti-SARS-CoV-2 research applications. It suppresses renal cancer cell proliferation and invasion via PI3K-AKT-mTOR pathway modulation and induces non-caspase-dependent apoptosis in neuroblastoma cells by inhibiting ER calcium release.
Product Specifications
CAS Number
172907-03-8
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Sigma-2 agonist
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Water (up to 5 mg/ml)
Smiles
COC1=CC=CC2=C1CCCC2CCCN3CCN (C4CCCCC4) CC3.Cl.Cl
Molecular Formula
C24H38N2O·2HCl
Molecular Weight
443.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-Cyclohexyl-4-[3- (1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl) propyl]piperazine, dihydrochloride
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