PD180970
PD180970 is a potent small molecule inhibitor targeting Bcr-Abl, Src, and Kit kinases, with respective IC50 values of 5 nM, 0.8 nM, and 50 nM. It is a valuable research tool for in vitro and in vivo studies investigating the mechanisms and treatment of chronic myelogenous leukemia and related tyrosine kinase-driven pathologies.
Product Specifications
CAS Number
287204-45-9
Product Name Alternative
CKit, BcrAbl, Bcr-Abl, Kit, PD 180970, PD180970, PD-180970, Src
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.47% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:1 mg/mL (2.33 mM) ; DMSO:90 mg/mL (209.66 mM)
Smiles
Cc1cc (Nc2ncc3cc (-c4c (Cl) cccc4Cl) c (=O) n (C) c3n2) ccc1F
Molecular Formula
C21H15Cl2FN4O
Molecular Weight
429.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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