PIT-1
PIT-1 is a selective PIP3 antagonist that suppresses the PI3K/Akt pathway by blocking PIP3 binding to Akt's PH domain. This inhibition induces apoptosis and reduces cancer cell viability, making it a valuable tool for studying oncogenic signalling in both cellular and animal models of cancer.
Product Specifications
CAS Number
53501-41-0
Product Name Alternative
PIT 1, PIT1, PIT-1
Field of Research
Cell Biology
Purity
>98%
Bioactivity
PH Domain antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 3 mg/ml) .
Smiles
O=C (NC (=S) NC1=CC (=CC (Cl) =C1O) N (=O) =O) C=2C=CC=CC2
Molecular Formula
C14H10ClN3O4S
Molecular Weight
351.76
Storage Conditions
RT
Notes
For research use only.
Other Product Names
N-[[ (3-Chloro-2-hydroxy-5-nitrophenyl) amino]thioxomethyl]benzamide
Available Sizes
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