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PIT

PIT (2,2'-Pyridylisatogen tosylate) is a potent, non-competitive P2Y1 receptor antagonist (IC50=0.14 μM) that does not inhibit nucleotide binding. Its utility extends to in vitro and in vivo research on purinergic signaling in respiratory diseases, including studies related to chronic bronchitis and asthma pathophysiology.

Product Specifications

CAS Number

56583-49-4

Product Name Alternative

2,2'-Pyridylisatogen tosylate, 2,2'-Pyridylisatogen Tosylate, P2Y, P2Y Receptor, P2YReceptor, PIT

Field of Research

Neuroscience, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Purity

98.63% (May vary between batches)

Solubility

DMSO:75 mg/mL (189.19 mM) ;10% DMSO+90% Saline:3.3 mg/mL (8.32 mM) ; Ethanol:< 5.95 mg/mL

Smiles

Cc1ccc (cc1) S (O) (=O) =O.[O-][N+]1=C (C (=O) c2ccccc12) c1ccccn1

Molecular Formula

C20H16N2O5S

Molecular Weight

396.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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