PIT
PIT (2,2'-Pyridylisatogen tosylate) is a potent, non-competitive P2Y1 receptor antagonist (IC50=0.14 μM) that does not inhibit nucleotide binding. Its utility extends to in vitro and in vivo research on purinergic signaling in respiratory diseases, including studies related to chronic bronchitis and asthma pathophysiology.
Product Specifications
CAS Number
56583-49-4
Product Name Alternative
2,2'-Pyridylisatogen tosylate, 2,2'-Pyridylisatogen Tosylate, P2Y, P2Y Receptor, P2YReceptor, PIT
Field of Research
Neuroscience, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
98.63% (May vary between batches)
Solubility
DMSO:75 mg/mL (189.19 mM) ;10% DMSO+90% Saline:3.3 mg/mL (8.32 mM) ; Ethanol:< 5.95 mg/mL
Smiles
Cc1ccc (cc1) S (O) (=O) =O.[O-][N+]1=C (C (=O) c2ccccc12) c1ccccn1
Molecular Formula
C20H16N2O5S
Molecular Weight
396.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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