PPY A
PPY A is a potent small molecule inhibitor effective against both wild-type and T315I mutant forms of Abl kinase, with IC50 values of 20 nM and 9 nM, respectively. It suppresses the proliferation of cells transformed by Bcr-Abl, making it a valuable tool for in vitro studies of drug-resistant chronic myeloid leukemia.
Product Specifications
CAS Number
875634-01-8
Product Name Alternative
PPY A, BcrAbl, Bcr-Abl1
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.22% (May vary between batches)
Solubility
DMSO:10 mg/mL (26.85 mM)
Smiles
O=C (C1=CN=CC (=C1) C2=CN=C3NC=C (C=4C=CC=CC4OC) C3=C2) N (C) C
Molecular Formula
C22H20N4O2
Molecular Weight
372.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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