LHF-535
LHF-535 is an antiviral agent extracted from patent WO2013123215A2, Compound 38, has EC50s of [1].
Product Specifications
CAS Number
[1450929-77-7]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Arenavirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
Neuroscience-Neuromodulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lhf-535.html
Purity
99.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C)(C)C1=CC=C(/C=C\C2=CC=C3C(N=CN3C4=CC=C(OC(C)C)C=C4)=C2)C=C1
Molecular Formula
C27H28N2O2
Molecular Weight
412.52
Precautions
H315, H319, H320
References & Citations
[1]Dongcheng Dai, et al. Antiviral drugs for treatment of arenavirus infection. WO2013123215A2.|[2]Madu IG, et al. A potent Lassa virus antiviral targets an arenavirus virulence determinant. PLoS Pathog. 2018 Dec 21;14 (12) :e1007439.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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