SC 19220
SC 19220 is a selective EP1 receptor antagonist that blocks prostaglandin E2 signaling. It suppresses osteoclast formation by inhibiting the RANK/RANKL pathway in precursor cells, making it a useful research tool for studying bone resorption in osteoporosis and inflammatory bone disease models.
Product Specifications
CAS Number
19395-87-0
Product Name Alternative
SC 19220, SC19220, SC-19220
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.95 mM) ; DMSO:80 mg/mL (241.15 mM)
Smiles
O=C (NNC (=O) C) N1C2=CC (Cl) =CC=C2OC=3C=CC=CC3C1
Molecular Formula
C16H14ClN3O3
Molecular Weight
331.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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