SF 11
SF 11 is a brain-penetrant small molecule antagonist of the neuropeptide Y Y2 receptor, exhibiting an IC50 of 199 nM. It demonstrates antidepressant-like efficacy in preclinical models, supporting its use in neuroscience research for studying mood disorders and neuropeptide signaling in both in vitro and in vivo experimental systems.
Product Specifications
CAS Number
443292-81-7
Product Name Alternative
NPY Y2, SF11, SF-11, SF 11
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.54% (May vary between batches)
Solubility
Ethanol:< 22.33 mg/mL; DMSO:40 mg/mL (89.57 mM)
Smiles
C (O) (C1CCN (C (NC2=CC=C (OCC) C=C2) =S) CC1) (C3=CC=CC=C3) C4=CC=CC=C4
Molecular Formula
C27H30N2O2S
Molecular Weight
446.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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